Hello @Dean204 buddy its better you change your Vista OS to Windows 7 and also it depends on your configuration.
Before I also use Mcafee than I switch into Windows Defender (Microsoft Antivirus Software) still I'm using it never got any issue.
Old Laptop
I've disabled Windows Defender because it keeps flagging my own programs and programs I know are safe, as viruses. Doesn't even ask sometimes if you want it removed.
Anti-virus software is useful for less savvy computer users who don't write code, the problem is that most of the time when Microsoft think they found a virus they're really just guessing or assuming it wasn't written by the computer user.
Anti-virus software is useful for less savvy computer users who don't write code, the problem is that most of the time when Microsoft think they found a virus they're really just guessing or assuming it wasn't written by the computer user.